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AJ Mellor. Anaesthesia in Austere Environments.

This review will examine the possibilities for providing anaesthesia for casualties in challenging situations.There is a limited evidence base on which to draw as most anaesthetists faced with such problems will generate their own solution based on experience and personal preference. Military personnel are perhaps more likely to encounter these challenges and may be trained anaesthetists or jun...

Mechanism of microtubule stabilization by taccalonolide AJ

As a major component of the cytoskeleton, microtubules consist of αβ-tubulin heterodimers and have been recognized as attractive targets for cancer chemotherapy. Microtubule-stabilizing agents (MSAs) promote polymerization of tubulin and stabilize the polymer, preventing depolymerization. The molecular mechanisms by which MSAs stabilize microtubules remain elusive. Here we report a 2.05 Å cryst...

Inferring AJ Types for Concurrent Libraries

Data-centric synchronization advocates data-based synchronization as opposed to control-based synchronization. It is more intuitive and can make correct concurrent programming easier. Dolby et al. [9] proposed AJ, a type system for data-centric synchronization, and showed that Java programs can be refactored into AJ. Unfortunately, programmers still have to add synchronization constructs manual...

AJ Mellor. Anaesthesia in Austere Environments.

This review will examine the possibilities for providing anaesthesia for casualties in challenging situations.There is a limited evidence base on which to draw as most anaesthetists faced with such problems will generate their own solution based on experience and personal preference. Military personnel are perhaps more likely to encounter these challenges and may be trained anaesthetists or jun...